isometheptene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1496 | 503-01-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03AX10 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Other drugs for functional gastrointestinal disorders |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Migraine | off-label use | 37796009 | DOID:6364 |
| Vascular headache | off-label use | 128187005 | |
| Tension-type headache | off-label use | 398057008 | |
| Necrotizing enterocolitis in fetus OR newborn | contraindication | 2707005 | |
| Alcoholism | contraindication | 7200002 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Glaucoma | contraindication | 23986001 | DOID:1686 |
| Acute cerebrovascular insufficiency | contraindication | 29322000 | |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Acute nephropathy | contraindication | 58574008 | |
| Hepatic failure | contraindication | 59927004 | |
| Poisoning by acetaminophen | contraindication | 70273001 | |
| Agoraphobia | contraindication | 70691001 | DOID:593 |
| Seizure disorder | contraindication | 128613002 | |
| Obsessive-compulsive disorder | contraindication | 191736004 | DOID:10933 |
| Insomnia | contraindication | 193462001 | |
| Impaired renal function disorder | contraindication | 197663003 | |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Panic disorder | contraindication | 371631005 | DOID:594 |
| Peripheral vascular disease | contraindication | 400047006 | |
| Myocardial ischemia | contraindication | 414795007 | DOID:3393 |
| Myocardial infarction in recovery phase | contraindication | 418044006 | |
| Organic Cardiac Disease | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.72 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07097 | KEGG_DRUG |
| 7492-31-1 | SECONDARY_CAS_RN |
| 4018809 | VANDF |
| C0064007 | UMLSCUI |
| CHEBI:134765 | CHEBI |
| CHEMBL1697841 | ChEMBL_ID |
| DB06706 | DRUGBANK_ID |
| CHEMBL2355839 | ChEMBL_ID |
| 22297 | PUBCHEM_CID |
| 576 | INN_ID |
| C008192 | MESH_SUPPLEMENTAL_RECORD_UI |
| Y7L24THH6T | UNII |
| 104994 | RXNORM |
| 4928 | MMSL |
| d03077 | MMSL |
| 001759 | NDDF |
| 001762 | NDDF |
| 116516007 | SNOMEDCT_US |
| 387302004 | SNOMEDCT_US |
| 54824008 | SNOMEDCT_US |
Pharmaceutical products:
None